US PATENT SUBCLASS 530 / 388.2
.~.~.~.~.~ Binds microorganism or normal or mutant component or product thereof (e.g., animal cell, cell-surface antigen, secretory product, etc.)


Current as of: June, 1999
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530 /   HD   CHEMISTRY: NATURAL RESINS OR DERIVATIVES; PEPTIDES OR PROTEINS; LIGNINS OR REACTION PRODUCTS THEREOF

350  DF  PROTEINS, I.E., MORE THAN 100 AMINO ACID RESIDUES {14}
380  DF  .~ Blood proteins or globulins, e.g., proteoglycans, platelet factor 4, thyroglobulin, thyroxine, etc. {3}
386  DF  .~.~ Globulins {4}
387.1  DF  .~.~.~ Immunoglobulin, antibody, or fragment thereof, other than immunoglobulin antibody, or fragment thereof that is conjugated or absorbed {9}
388.1  DF  .~.~.~.~ Monoclonal {3}
388.2.~.~.~.~.~ Binds microorganism or normal or mutant component or product thereof (e.g., animal cell, cell-surface antigen, secretory product, etc.) {12}
388.21  DF  .~.~.~.~.~.~> Binds nucleic acid or derivative or component thereof (e.g., DNA, RNA, DNA-RNA hybrid, nucleotide, nucleoside, carcinogen-DNA adduct, etc.)
388.22  DF  .~.~.~.~.~.~> Binds receptor (e.g., transferrin receptor, Fc receptor, dihydropyridine receptor, IL-2 receptor, etc.)
388.23  DF  .~.~.~.~.~.~> Binds lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, or intercellular mediator specific for a hematopoietic cell (e.g., interleukin, interferon, erythropoietin, etc.)
388.24  DF  .~.~.~.~.~.~> Binds hormone or other secreted growth regulatory factor, differentiation factor, intercellular mediator, or neurotransmitter (e.g., insulin, human chorionic gonadotropin, intragonadal regulatory protein, Mullerian inhibiting substance, inhibin, epidermal growth factor, nerve growth factor, dopamine, norepinephrine, etc.)
388.25  DF  .~.~.~.~.~.~> Binds plasma protein, serum protein, or fibrin (e.g., clotting factor, fibrinolytic factor, complement factor, immunoglobulin, apolipoprotein, etc.)
388.26  DF  .~.~.~.~.~.~> Binds enzyme
388.3  DF  .~.~.~.~.~.~> Binds virus or component or product thereof (e.g., virus-associated antigen, etc.) {1}
388.4  DF  .~.~.~.~.~.~> Binds bacterium or similar microorganism or component or product thereof (e.g., Stretococcus, Legionella, Mycoplasma, bacterium-associated antigen, exotoxin, etc.)
388.5  DF  .~.~.~.~.~.~> Binds fungus or plant cell or component or product thereof (e.g., fungus-associated antigen, etc.)
388.6  DF  .~.~.~.~.~.~> Binds parasitic protozoan or metazoan cell or component or product thereof (e.g., Dirofilaria, Eimeria, Coccidia, Trichinella, parasite cell-surface antigen, etc.)
388.7  DF  .~.~.~.~.~.~> Binds hematopoietic cell or component or product thereof (e.g., erythrocyte granulocyte, macrophage, monocyte, platelet, myelogenous leukemia cell, bone marrow stem cell, granulocytic cell-surface antigen, hemoglobin, thrombospondin, glycophorin, etc.) {1}
388.8  DF  .~.~.~.~.~.~> Binds cancer cell or component or product thereof (e.g., cell-surface antigen, etc.) {1}


DEFINITION

Classification: 530/388.2

Binds microorganism or normal or mutant component or product thereof (e.g., animal cell, cell-surface antigen, secretory product, etc.):

(under subclass 388.1) Subject matter involving a monoclonal antibody or antigen-binding fragment thereof whose antigen-binding site(s) will combine with an integral or isolated part of a micro-organism, or with a substance shed or secreted by a micro-organism, or with a chemically-altered component of a microorganism, or with a chemically-altered substance shed or secreted by a micro-organism.

(1) Note. A micro-organism, for the purpose of this and indented subclasses, is a cell of a multicellular organism, a single-celled organism, a virus, or other intracellular organism.

(2) Note. A mutant or chemically-altered component or product of a micro-organism may be made by chemical synthesis or chemical modification or by expression of a cloned altered gene.

(3) Note. Monoclonal antibodies or fragments thereof that bind a mutant or chemically-altered component or product of a micro-organism are proper for the subclass that provides for monoclonal antibodies that bind the corresponding normal component or product.