US PATENT SUBCLASS 530 / 388.24
.~.~.~.~.~.~ Binds hormone or other secreted growth regulatory factor, differentiation factor, intercellular mediator, or neurotransmitter (e.g., insulin, human chorionic gonadotropin, intragonadal regulatory protein, Mullerian inhibiting substance, inhibin, epidermal growth factor, nerve growth factor, dopamine, norepinephrine, etc.)

Current as of: June, 1999
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530 /   HD   CHEMISTRY: NATURAL RESINS OR DERIVATIVES; PEPTIDES OR PROTEINS; LIGNINS OR REACTION PRODUCTS THEREOF

350  DF  PROTEINS, I.E., MORE THAN 100 AMINO ACID RESIDUES {14}
380  DF  .~ Blood proteins or globulins, e.g., proteoglycans, platelet factor 4, thyroglobulin, thyroxine, etc. {3}
386  DF  .~.~ Globulins {4}
387.1  DF  .~.~.~ Immunoglobulin, antibody, or fragment thereof, other than immunoglobulin antibody, or fragment thereof that is conjugated or absorbed {9}
388.1  DF  .~.~.~.~ Monoclonal {3}
388.2  DF  .~.~.~.~.~ Binds microorganism or normal or mutant component or product thereof (e.g., animal cell, cell-surface antigen, secretory product, etc.) {12}
388.24.~.~.~.~.~.~ Binds hormone or other secreted growth regulatory factor, differentiation factor, intercellular mediator, or neurotransmitter (e.g., insulin, human chorionic gonadotropin, intragonadal regulatory protein, Mullerian inhibiting substance, inhibin, epidermal growth factor, nerve growth factor, dopamine, norepinephrine, etc.)

DEFINITION

Classification: 530/388.24

Binds hormone or other secreted growth regulatory factor, differentiation factor, intercellular mediator, or neurotransmitter (e.g., insulin, human chorionic gonadotropin, intragonadal regulatory protein, mullerian inhibiting substance, inhibin, epidermal growth factor, nerve growth factor, dopamine, norepinephrine, etc.):

(under subclass 388.2) Subject matter involving a monoclonal antibody or antigen-binding fragment thereof whose antigen-binding site(s) will combine with a neurotransmitter, with a hormone, or with any other secreted growth regulatory factor, differentiation factor, or intercellular mediator that targets cells other than hematopoietic cells.

(1) Note. The term "growth regulatory factor" is meant to encompass any secretory factor that is growth- stimulatory or growth-inhibitory; e.g., that will stimulate or inhibit clonal expansion of cells.

(2) Note. The term "differentiation factor" is meant to encompass any secretory factor that causes cells to progress from a relatively undifferentiated state to a more differentiated state, wherein said progression may include clonal expansion.

(3) Note. The term "intercellular mediator" is meant to encompass any secretory factor that affects cellular functions such as chemotaxis, etc.