US PATENT SUBCLASS 530 / 388.23-- .~.~.~.~.~.~ Binds lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, or intercellular mediator specific for a hematopoietic cell (e.g., interleukin, interferon, erythropoietin, etc.)

US PATENT SUBCLASS 530 / 388.23
.~.~.~.~.~.~ Binds lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, or intercellular mediator specific for a hematopoietic cell (e.g., interleukin, interferon, erythropoietin, etc.)

Current as of: June, 1999
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530 /	HD	CHEMISTRY: NATURAL RESINS OR DERIVATIVES; PEPTIDES OR PROTEINS; LIGNINS OR REACTION PRODUCTS THEREOF

350	DF	PROTEINS, I.E., MORE THAN 100 AMINO ACID RESIDUES {14}
380	DF	.~ Blood proteins or globulins, e.g., proteoglycans, platelet factor 4, thyroglobulin, thyroxine, etc. {3}
386	DF	.~.~ Globulins {4}
387.1	DF	.~.~.~ Immunoglobulin, antibody, or fragment thereof, other than immunoglobulin antibody, or fragment thereof that is conjugated or absorbed {9}
388.1	DF	.~.~.~.~ Monoclonal {3}
388.2	DF	.~.~.~.~.~ Binds microorganism or normal or mutant component or product thereof (e.g., animal cell, cell-surface antigen, secretory product, etc.) {12}
388.23		.~.~.~.~.~.~ Binds lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, or intercellular mediator specific for a hematopoietic cell (e.g., interleukin, interferon, erythropoietin, etc.)

DEFINITION

Classification: 530/388.23

Binds lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, or intercellular mediator specific for a hematopoietic cell (e.g., interleukin, interferon, erythropoietin, etc.):

(under subclass 388.2) Subject matter involving a monoclonal antibody or antigen-binding fragment thereof whose antigen-binding site(s) will combine with a lymphokine, cytokine, or any other secreted growth stimulatory factor, growth inhibitory factor, differentiation factor, or intercellular mediator that targets any type(s) of hematopoietic cells.

(1) Note. The term "growth regulatory factor" is meant to encompass any secretory factor that is growth-stimulatory or growth-inhibitory; i.e., that will stimulate or inhibit clonal expansion of cells.

(2) Note. The term "differentiation factor" is meant to encompass any secretory factor that causes cells to progress from a relatively undifferentiated state to a more differentiated state, wherein said progression may include clonal expansion.

(3) Note. The term "intercellular mediator" is meant to encompass any secretory factor that affects cellular functions such as chemotaxis, etc.

(4) Note. See Patent Classification Definitions for Class 424, subclass 85.1, for examples of lymphokines and cytokines.

(5) Note. Hematopoietic cells are considered to be bone marrow stem cells and cells derived from bone marrow stem cells, including cells at any stage of differentiation from progenitor cells to mature erythrocytes, granulocytes, lymphocytes, etc., both normal and neoplastic.