US PATENT SUBCLASS 530 / 389.2
.~.~.~.~.~ Binds hormone, lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, intercellular mediator, or neurotransmitter (e.g., insulin, human chorionic gonadotropin, glucagon, cardiodilatin, interleukin, interferon, norepinephrine, epinephrine, acetylcholine, etc.)

Current as of: June, 1999
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530 /   HD   CHEMISTRY: NATURAL RESINS OR DERIVATIVES; PEPTIDES OR PROTEINS; LIGNINS OR REACTION PRODUCTS THEREOF

350  DF  PROTEINS, I.E., MORE THAN 100 AMINO ACID RESIDUES {14}
380  DF  .~ Blood proteins or globulins, e.g., proteoglycans, platelet factor 4, thyroglobulin, thyroxine, etc. {3}
386  DF  .~.~ Globulins {4}
387.1  DF  .~.~.~ Immunoglobulin, antibody, or fragment thereof, other than immunoglobulin antibody, or fragment thereof that is conjugated or absorbed {9}
389.1  DF  .~.~.~.~ Polyclonal antibody or immunogloblin of identified binding specificity {7}
389.2.~.~.~.~.~ Binds hormone, lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, intercellular mediator, or neurotransmitter (e.g., insulin, human chorionic gonadotropin, glucagon, cardiodilatin, interleukin, interferon, norepinephrine, epinephrine, acetylcholine, etc.)

DEFINITION

Classification: 530/389.2

Binds hormone, lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, intercellular mediator, or neurotransmitter (e.g., insulin, human chorionic gonadotropin, glucagon, cardiodilatin, interleukin, interferon, norepinephrine, epinephrine, acetylcholine, etc.):

(under subclass 389.1) Subject matter involving a polyclonal antibody or immunoglobulin or antigen-binding fragment thereof whose antigen-binding site(s) will combine with a hormone, lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, intercellular mediator, or neurotransmitter.

(1) Note. The term "growth regulatory factor" is meant to encompass any secretory factor that is growth-stimulatory or growth-inhibitory; i.e., that will stimulate or inhibit clonal expansion of cells.

(2) Note. The term "differentiation factor" is meant to encompass any secretory factor that causes cells to progress from a relatively undifferentiated state to a more differentiated state, wherein said progression may include clonal expansion.

(3) Note. The term "intercellular mediator" is meant to encompass any secretory factor that affects cellular functions such as chemotaxis, etc.

(4) Note. See Patent Classification Definitions for Class 424, subclass 85.1 for examples of lymphokines and cytokines.

(5) Note. This subclass includes polyclonal antibodies, immunoglobulins, or fragments thereof that bind any growth regulatory factor, differentiation factor, or intercellular mediator that targets any type(s) of cells, including hematopoietic cells.

(6) Note. Hematopoietic cells are considered to be bone marrow stem cells and cells derived from bone marrow stem cells, including cells at any stage of differentiation from progenitor cells to mature erythrocytes, granulocytes, lymphocytes, etc., both normal and neoplastic.