US PATENT SUBCLASS 435 / 441
.~ Mutation employing a chemical mutagenic agent

Current as of: June, 1999
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435 /   HD   CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY

440  DF  PROCESS OF MUTATION, CELL FUSION, OR GENETIC MODIFICATION {6}
441.~ Mutation employing a chemical mutagenic agent {4}
442  DF  .~.~> By replacement of standard nucleic acid base with base analog (e.g., 5-bromouracil, etc.)
443  DF  .~.~> By use of intercalating agent (e.g., acridine orange, etc.)
444  DF  .~.~> By use of alkylating agent (e.g., nitrosoguanidine, etc.)
445  DF  .~.~> By use of oxidative deamination agent (e.g., nitrous acid, etc.)

DEFINITION

Classification: 435/441

Mutation employing a chemical mutagenic agent:

(under subclass 440) Processes wherein structural change in a gene is effected by a reaction of an animal, plant, or microbial cell with a chemical compound or composition.

(1) Note. Chemical or enzymatic alteration of a nucleic acid outside of a cell, followed my introduction of said nucleic acid into a cell, e.g., in vitro mutagenesis or site-directed mutagenesis, etc. is not proper for this or indented subclasses. See the SEE OR SEARCH THIS CLASS, SUBCLASS references below.

(2) Note. Enzymatic alteration of a nucleic acid without introduction into a cell is not proper for this subclass.

SEE OR SEARCH THIS CLASS, SUBCLASS:

91.1+, for enzymatically altering a nucleic acid without further introducing it into a cell or microorganism.

375, for treating an animal cell with an antisense nucleic acid thereby altering cell metabolism or physiology.

455+, for processes of introducing nucleic acid into or rearrangement of nucleic acid within an animal cell. 468+, for processes of introducing nucleic acid into or rearrangement of nucleic acid within a plant cell.

471+, for processes of introducing nucleic acid into or rearrangement of nucleic acid within a microorganism.