US PATENT SUBCLASS 435 / 442-- .~.~ By replacement of standard nucleic acid base with base analog (e.g., 5-bromouracil, etc.)

US PATENT SUBCLASS 435 / 442
.~.~ By replacement of standard nucleic acid base with base analog (e.g., 5-bromouracil, etc.)

Current as of: June, 1999
Click HD for Main Headings
Click for All Classes

Internet Version by PATENTEC © 1999 Terms of Use

435 /	HD	CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY

440	DF	PROCESS OF MUTATION, CELL FUSION, OR GENETIC MODIFICATION {6}
441	DF	.~ Mutation employing a chemical mutagenic agent {4}
442		.~.~ By replacement of standard nucleic acid base with base analog (e.g., 5-bromouracil, etc.)

DEFINITION

Classification: 435/442

By replacement of standar nucleic acid base with base analog (e.g., 5-bromouracil, etc.):

(under subclass 441) Processes involving a compound which is incorporated into a DNA strand by replacing a normally present deoxynucleotide triphosphate thereby altering its base-pair sequence.

(1) Note. Examples of base analogs include 5-bromouracil, 5-fluorouracil, 5-bromodeoxyuridine, 5-ethyl-2'-deoxyuridine, 5-iodo-2'-deoxyuridine, and 6-thioguanine.

(2) Note. The mode of action of the base analog is that it substitutes for a standard nucleic acid base during replication and causes a new base pair to appear in daughter cells in a later generation.