US PATENT SUBCLASS 530 / 320
.~.~ Bacitracin; related peptides


Current as of: June, 1999
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530 /   HD   CHEMISTRY: NATURAL RESINS OR DERIVATIVES; PEPTIDES OR PROTEINS; LIGNINS OR REACTION PRODUCTS THEREOF

300  DF  PEPTIDES OF 3 TO 100 AMINO ACID RESIDUES {29}
317  DF  .~ Cyclic peptides {3}
320.~.~ Bacitracin; related peptides


DEFINITION

Classification: 530/320

Bacitracin; related peptides:

(under subclass 317) Peptides containing at least half the amino acid sequence of Bacitracin.

(1) Note. Bacitracins are produced by various strains of Bacillus Licheniformis and Bacillus stubilis.

(2) Note. Bacitracin. Synonyms. Ayfivin, Baciguent, Baci-Jel, Bacitek Ointment, Paretracin, Penitracin, Topitracin, Zotraacin, Baciliguin, Bacillichin. CA Registry Number of unmodified form: 1405-87-4 [figure]

(4) Note. The most important of the group is bacitracin A, which contains an unusual thiazoline structure synthesized from the N-terminal isoleucine and the neighboring cysteine. Bacitracin F is a rearrangment product of bacitracin A in which the amino group of the heteroproduct is oxidatively removed and the thiazoline ring system is dehydrated. [figure]