US PATENT SUBCLASS 530 / 319
.~.~.~ Polymyxin; related peptides

Current as of: June, 1999
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530 /   HD   CHEMISTRY: NATURAL RESINS OR DERIVATIVES; PEPTIDES OR PROTEINS; LIGNINS OR REACTION PRODUCTS THEREOF

300  DF  PEPTIDES OF 3 TO 100 AMINO ACID RESIDUES {29}
317  DF  .~ Cyclic peptides {3}
318  DF  .~.~ The cyclisation occurring through the 4-amino radical of 2,4-diamino butanoic acid {1}
319.~.~.~ Polymyxin; related peptides

DEFINITION

Classification: 530/319

Polymyxin; related peptides:

(under subclass 318) Peptides containing at least half the

amino acid residues of the polypeptide produced by Bacillus polymyxa and possessing antibiotic activity against Gram-negative bacteria.

(1) Note. Polymyxins are heteromeric, homodetic cyclic peptides. Polymyxins designated A, B, C, D, E and M are known.

(2) Note. Synonyms. Syno-colistin.

(3) Note. CA Registry Number of unmodified form: 1406-11-7 [figure]