FOR PREEXISTING IMMUNE COMPLEX OR AUTO-IMMUNE DISEASE:
(under the class definition) Subject matter involving immunoassay for antigens, antibodies or immune complexes associated with autoimmune disease.
(1) Note. This subclass includes immunohistopathology testing.
(2) Note. Autoimmune disease includes: (a) Systemic Rheumatic diseases [(1) Systemic lupus erythematosus; (2) Progressive systemics clerosia; (3) Chronic discoid lupus; (4) Mixed connective tissue disease (MCTD)] (b) Rheumatoid Arthritis; (c) Kidney diseases resulting from reaction of antibodies with renal basement membrane, or the formation of circulating immune complex glomeralonephritis; (d) Hashmotos disease (chronic thyroiditis); (e) Diseases involving antibodies to tissue specific antigens [1. Mitrochrondrial antigens (antibodies found in primary biliary cirrhosis). 2. Smooth muscle antigens, i.e., antibodies which may be demonstrated in some infectious disease such as viral hepatitis, yellow fever and infectious mononucleosis and in some malignancies such as carcinoma of the ovary and malignant melanoma and in some types of cirrhosis. 3. Gastric Parietal Cells - antibodies to intracytoplasmic antigens of gastric parietal cells, to the B12 binding site of intrinsic factor and to the intrinsic factor B12 complex may be found in patients with pernicious anemia.] (f) Skin Diseases [1. Vesiculoballous skin diseases-pemphigus, pemphigoids, dermatitis herpeti formis, herpes gestatenis; 2. Cutaneous forms of lupus erythematosis vasculitis (rheumatoid vasculitis)] (g) Human sperm antibodies.
