US PATENT SUBCLASS 435 / 7.1
.~ Involving antigen-antibody binding, specific binding protein assay or specific ligand-receptor binding assay

Current as of: June, 1999
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435 /   HD   CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY

4  DF  MEASURING OR TESTING PROCESS INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITION OR TEST STRIP THEREFORE; PROCESSES OF FORMING SUCH COMPOSITION OR TEST STRIP {15}
7.1.~ Involving antigen-antibody binding, specific binding protein assay or specific ligand-receptor binding assay {9}
7.2  DF  .~.~> Involving a micro-organism or cell membrane bound antigen or cell membrane bound receptor or cell membrane bound antibody or microbial lysate {4}
7.4  DF  .~.~> To identify an enzyme or isoenzyme
7.5  DF  .~.~> Involving avidin-biotin binding
7.6  DF  .~.~> Involving a modified enzyme (e.g., abzyme, recombinant, chemically altered, etc.)
7.7  DF  .~.~> Assay in which a label present is an apoenzyme, prosthetic group, or enzyme cofactor
7.71  DF  .~.~> Assay in which a label present is an enzyme inhibitor or functions to alter enzyme activity
7.72  DF  .~.~> Assay in which a label present is an enzyme substrate or substrate analogue
7.8  DF  .~.~> Involving nonmembrane bound receptor binding or protein binding other than antigen-antibody binding
7.9  DF  .~.~> Assay in which an enzyme present is a label {2}

DEFINITION

Classification: 435/7.1

Involving antigen-antibody binding, specific binding protein assay, or specific ligand-receptor binding assay:

(under subclass 4) Subject matter in which a measurement or test utilizes an enzyme or microorganism or plant or animal cells in an antibody binding, specific binding protein or other specific ligand-receptor binding test or assay.

(1) Note. Cross-Reference Art Collections 960 through 975 provide for different aspects of the subject matter of this and the indented subclasses.

(2) Note. The enzyme or microorganism may function for example, as an antigen, separating agent or detection label in a test or assay.

(3) Note. Subject matter directed to identifying a specific enzyme in a microorganism or tissue is appropriate for subclass 7.4 below, however, determining an enzyme as an indirect indication of a specific microorganism being present is appropriate for the microorganism subclass.

(4) Note. Subject matter directed to determining the presence of a specific microorganism is appropriate for the specific microbial subclass below. For example, an assay for determining a bacteria in an animal tissue sample is appropriate for the bacteria subclass rather than the animal cell subclass.

(5) Note. An indirect microbial determination, such as a determination of a microbial product as an indication of the presence of the microbe, is appropriate for the microbial subclasses below. However, it is strongly suggested that a patent containing such an indirect microbial determination be cross-referenced to the subclass appropriate for the assay of the product of the microbe.

(6) Note. Terminology used in this and the indented subclasses is found at the end of this subclass definition.

SEE OR SEARCH THIS CLASS, SUBCLASS:

5, for processes in which a virus is involved, as for example, as an antigen.

174+, for immobilized enzymes.

183+, for enzymes, per se, and methods of isolating enzymes.

188, for enzyme conjugates.

SEE OR SEARCH CLASS

424, Drug, Bio-Affecting and Body Treating Compositions,

184.1+, for methods of immunizing with an antigen to induce protective immunity in vivo. Class 424 provides for in vivo antigen-antibody tests.

436, Chemistry: Analytical and Immunological Testing, for a measurement or test involving antigen-antibody tests and other ligand-receptor binding tests for the identification of chemical species that do not involve a microorganism or enzyme.

530, Chemistry, Natural Resins or Derivatives Peptides or Proteins; Lignins or Reaction Products Thereof,

387+, for antibodies, per se, subclasses 403+ for protein antigens or the use of antigenic proteins as an immunogenic carrier for a hapten, subclass 413 for immunological separation and affinity chromatography, cross-reference art collections 806 for antigenic peptides or protein, and 807 for hapten conjugated with peptide or protein, and 808 for monoclonal antibodies.

600, and 604, Surgery, provides for methods including the use of claimed specific structure adapted to be placed on or in the living body and further include diagnostic or therapeutic methods and apparatus when the only disclosed utility is for diagnosis or treatment of a living body. ANALYTE

The compound or composition to be measured.

SPECIFIC LIGAND-RECEPTOR BINDING ASSAY

The interaction between a ligand material and a receptor which is specific to a class of compounds or a single compound.

EPITOPE

A single antigenic determinant portion of the antigen which combines with the antibody site.

LABEL

A member of a signal producing system which is usually bound to or incorporated in the ligand. Measurement of the label activity is an indication of the amount of unknown in the sample.

LIGAND

Any organic compound for which a receptor naturally exists or can be prepared; a linking or binding molecule.

RECEPTOR Any compound or composition capable of recognizing a particular spatial and polar organization of a molecule, i.e., epitopic site on an antigen. The receptor material can be isolated from a cellular material from a living body such as a membrane or organ and exhibits great specificity to the species to be tested for. A cell surface molecule which binds specifically to particular proteins or peptides in the fluid phase.