US PATENT SUBCLASS 435 / 456
.~.~ The polynucleotide is encapsidated within a virus or viral coat

Current as of: June, 1999
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435 /   HD   CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY

440  DF  PROCESS OF MUTATION, CELL FUSION, OR GENETIC MODIFICATION {6}
455  DF  .~ Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within an animal cell {11}
456.~.~ The polynucleotide is encapsidated within a virus or viral coat {1}
457  DF  .~.~.~> Helper virus is present

DEFINITION

Classification: 435/456

The polynucleotide is encapsidated within a virus or viral coat:

(under subclass 455) Processes wherein the nucleic acid which is to be introduced into the cell is surrounded, entirely or substantially, by viral coat protein when brought into contact or proximity to said cell.

(1) Note. Viral coat protein may be a protein with a naturally occurring, mutated or recombinantly modified sequence, or a protein which is an entirely synthetically designed sequence, provided that said protein forms an organized array around the nucleic acid and facilitates independent entry of said nucleic acid into said cell.