US PATENT SUBCLASS 424 / 158.1
.~ Binds hormone or other secreted growth regulatory factor, differentiation factor, or intercellular mediator (e.g., cytokine, vascular permeability factor, etc.); or binds serum protein, plasma protein, fibrin, or enzyme

Current as of: June, 1999
Click HD for Main Headings
Click for All Classes

Internet Version by PATENTEC © 1999      Terms of Use


424 /   HD   DRUG, BIO-AFFECTING AND BODY TREATING COMPOSITIONS

130.1  DF  IMMUNOGLOBULIN, ANTISERUM, ANTIBODY, OR ANTIBODY FRAGMENT, EXCEPT CONJUGATE OR COMPLEX OF THE SAME WITH NONIMMUNOGLOBULIN MATERIAL {18}
158.1.~ Binds hormone or other secreted growth regulatory factor, differentiation factor, or intercellular mediator (e.g., cytokine, vascular permeability factor, etc.); or binds serum protein, plasma protein, fibrin, or enzyme

DEFINITION

Classification: 424/158.1

Binds hormone or other secreted growth regulatory factor, differentiation factor, or intercellular mediator (e.g., cytokine, vascular permeability factor, etc.); or binds serum protein, plasma protein, fibrin, or enzyme:

(under subclass 130.1) Subject matter involving an antibody or antigen-binding fragment thereof whose antigen-binding site(s) will combine with a hormone or with any other secreted growth regulatory factor, differentiation factor, or intercellular mediator; or involving an antibody or antigen-binding fragment thereof whose antigen-binding site(s) will combine with a serum protein, a plasma protein, fibrin, or an enzyme.

(1) Note. The term "growth regulatory factor" is meant to encompass any secretory factor that is growth-stimulatory or growth-inhibitory (e.g., that will stimulate or inhibit clonal expansion of cells).

(2) Note. The term "differentiation factor" is meant to encompass any secretory factor that causes cells to progress from a relatively undifferentiated state to a more differentiated state, wherein said progression may include clonal expansion.

(3) Note. The term "intercellular mediator" is meant to encompass any secretory factor that affects cellular functions such as chemotaxis, etc.

(4) Note. Patents under the class definition with disclosures to antibodies or fragments thereof that bind proteins, including enzymes, that are members of plasma "activation systems"--including the clotting system, the fibrinolytic system, the bradykinin system, and the complement system--are proper for this subclass.

(5) Note. Patents under the class definition with disclosures to non-anti-idiotypic antibodies or fragments thereof that bind immunoglobulins are proper for this subclass, unless the antibodies specifically bind hematopoietic-cell-bound immunoglobulins, in which case, the patents are proper for subclass 173.1.

(6) Note. See patent classification definitions for Class 530, subclasses 380+, for examples of plasma and serum proteins.