US PATENT SUBCLASS 424 / 130.1
IMMUNOGLOBULIN, ANTISERUM, ANTIBODY, OR ANTIBODY FRAGMENT, EXCEPT CONJUGATE OR COMPLEX OF THE SAME WITH NONIMMUNOGLOBULIN MATERIAL

Current as of: June, 1999
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424 /   HD   DRUG, BIO-AFFECTING AND BODY TREATING COMPOSITIONS

130.1IMMUNOGLOBULIN, ANTISERUM, ANTIBODY, OR ANTIBODY FRAGMENT, EXCEPT CONJUGATE OR COMPLEX OF THE SAME WITH NONIMMUNOGLOBULIN MATERIAL {18}
131.1  DF  .~> Anti-idiotypic
132.1  DF  .~> Derived from transgenic multicellular eukaryote (e.g., plant, etc.)
133.1  DF  .~> Structurally-modified antibody, immunoglobulin, or fragment thereof (e.g., chimeric, humanized, CDR-grafted, mutated, etc.) {3}
137.1  DF  .~> Binds specifically-identified oligosaccharide structure
138.1  DF  .~> Binds expression product or fragment thereof of cancer-related gene (e.g., oncogene, proto-oncogene, etc.)
139.1  DF  .~> Binds antigen or epitope whose amino acid sequence is disclosed in whole or in part (e.g., binds specifically-identified amino acid sequence, etc.)
140.1  DF  .~> Extracorporeal or ex vivo removal of antibodies or immune complexes (e.g., removal of autoantibodies, etc.); or extracorporeal or ex vivo removal of antigen by antibodies (e.g., removal of cancer cells from bone marrow by antibodies, etc.)
141.1  DF  .~> Monoclonal antibody or fragment thereof (i.e., produced by any cloning technology) {8}
157.1  DF  .~> Derived from, or present in, food product (e.g., milk, colostrum, whey, eggs, etc.)
158.1  DF  .~> Binds hormone or other secreted growth regulatory factor, differentiation factor, or intercellular mediator (e.g., cytokine, vascular permeability factor, etc.); or binds serum protein, plasma protein, fibrin, or enzyme
159.1  DF  .~> Binds virus or component thereof {3}
163.1  DF  .~> Binds antigens of multiple bacterial species (e.g., multivalent antiserum that binds antigens of multiple bacterial species, etc.)
164.1  DF  .~> Binds bacterium or component thereof or substance produced by said bacterium {6}
171.1  DF  .~> Binds allergen or component thereof
172.1  DF  .~> Binds eukaryotic cell or component thereof or substance produced by said eukaryotic cell (e.g., honey, etc.) {2}
175.1  DF  .~> Binds hapten, hapten-carrier complex, or specifically-identified chemical structure (e.g., drug, etc.)
176.1  DF  .~> Free from infectious agents (e.g., viruses or bacteria removed or inactivated, etc.)
177.1  DF  .~> Reduced antigenicity, reduced ability to bind complement, or reduced numbers of activated complement components (e.g., free from aggregated, denatured, fragmented, or polymerized immunoglobulins; free from proteolytic enzymes, etc.)

DEFINITION

Classification: 424/130.1

IMMUNOGLOBULIN, ANTISERUM, ANTIBODY, OR ANTIBODY FRAGMENT, EXCEPT CONJUGATE OR COMPLEX OF THE SAME WITH NONIMMUNOGLOBULIN MATERIAL:

(under the class definition) Subject matter involving an immunoglobulin, an antiserum, an antibody, or an antibody

fragment, except a conjugate or a complex of the same with a nonimmunoglobulin material.

(1) Note. This subclass and indented subclasses provide for bioaffecting and body-treating compositions of immunoglobulins, antisera, antibodies, and antibody fragments.

(2) Note. This subclass and indented subclasses also provide for bioaffecting and body-treating methods of using immunoglobulins, antisera, antibodies, antibody fragments, and compositions thereof.

(3) Note. This subclass and indented subclasses also provide for methods of immunizing to produce antibodies for recovery, which antibodies are characterized as being useful as bioaffecting or body-treating agents (e.g., to provide passive immunity).

(4) Note. Methods of immunizing to produce protective immunity in vivo (i.e., for vaccination purposes) are provided for elsewhere.

(5) Note. Monoclonal and polyclonal antibodies, per se, are considered compounds and are provided for elsewhere.

(6) Note. Immunoglobulins are a class of globulins found in serum and other body fluids such as milk, saliva, tears, etc. All antibodies found in these fluids are immunoglobulins and can be characterized as having particular antigenic binding specificities. In addition, all immunoglobulins are presumably antibodies, even if their antigenic binding specificities have not been characterized. (7) Note. An antigen is a substance that elicits the production of antibodies, which antibodies, in turn, have binding specificity for that antigen.

(8) Note. Antibodies may be isolated from serum or the other body fluids in which they are found, or they may be isolated from the secretion products of cells grown in culture that express and secrete the products of antibody-encoding genes.

(9) Note. An antiserum is a serum that contains antibodies.

(10) Note. The major classes of immunoglobulins are IgG, IgM, IgA, IgD, and IgE. Subclasses of immunoglobulins also exist, notably the IgG1, IgG2a, IgG2b, IgG3, and IgG4 subclasses comprising the IgG class. IgY is similar to IgG and is found only in birds.

SEE OR SEARCH THIS CLASS, SUBCLASS:

1.49, and 1.53, for methods of using radiolabeled antibodies or compositions thereof for bioaffecting or body-treating

purposes and said compositions, per se.

9.1+, for methods of using antibodies or compositions thereof for in vivo testing or diagnosis and said compositions, per se.

178.1+, for bioaffecting or body-treating methods of using antibodies or fragments thereof that are conjugated to or complexed with nonimmunoglobulin material; bioaffecting or body-treating methods of using compositions of antibodies or fragments thereof, which antibodies or fragments thereof are conjugated to or complexed with nonimmunoglobulin material; and said compositions, per se.

184.1+, for methods of immunizing to produce protective immunity in vivo (i.e., for vaccination purposes)

SEE OR SEARCH CLASS

436, Chemistry: Analytical and Immunological Testing, 547, for compositions of polyclonal antibodies used in in vitro testing and subclass 548 for compositions of monoclonal antibodies used in in vitro testing.

530, Chemistry: Natural Resins or Derivatives; Peptides or Proteins; Lignins or Reaction Products Thereof,

387.1+, for immunoglobulins or antibodies, per se, processes of chemically modifying immunoglobulins or antibodies, and processes of separating or purifying immunoglobulins or antibodies.