US PATENT SUBCLASS 424 / 134.1
.~.~ Antibody, immunoglobulin, or fragment thereof fused via peptide linkage to nonimmunoglobulin protein, polypeptide, or fragment thereof (i.e., antibody or immunoglobulin fusion protein or polypeptide)

Current as of: June, 1999
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424 /   HD   DRUG, BIO-AFFECTING AND BODY TREATING COMPOSITIONS

130.1  DF  IMMUNOGLOBULIN, ANTISERUM, ANTIBODY, OR ANTIBODY FRAGMENT, EXCEPT CONJUGATE OR COMPLEX OF THE SAME WITH NONIMMUNOGLOBULIN MATERIAL {18}
133.1  DF  .~ Structurally-modified antibody, immunoglobulin, or fragment thereof (e.g., chimeric, humanized, CDR-grafted, mutated, etc.) {3}
134.1.~.~ Antibody, immunoglobulin, or fragment thereof fused via peptide linkage to nonimmunoglobulin protein, polypeptide, or fragment thereof (i.e., antibody or immunoglobulin fusion protein or polypeptide)

DEFINITION

Classification: 424/134.1

Antibody, immunoglobulin, or fragment thereof fused via peptide linkage to nonimmunoglobulin protein, polypeptide, or fragment thereof (i.e., antibody or immunoglobulin fusion protein or polypeptide):

(under subclass 133.1) Subject matter involving a fusion protein or fusion polypeptide that includes (a) an antibody, immunoglobulin, or fragment thereof fused directly via a peptide bond to a nonimmunoglobulin protein, polypeptide, or fragment thereof or (b) an antibody, immunoglobulin, or fragment thereof fused indirectly via a peptide linker to a nonimmunoglobulin protein, polypeptide, or fragment thereof, which fusion protein or polypeptide is the expression product of a gene fusion.

(1) Note. A gene fusion is a nucleic acid sequence that encodes the complete or partial amino acid sequences of two or more proteins or polypeptides in contiguous fashion, or in

noncontiguous fashion, wherein the expressed sequence is ultimately processed to yield the desired fusion protein.

SEE OR SEARCH THIS CLASS, SUBCLASS:

178.1+, for an immunoglobulin or immunoglobulin fragment joined to a nonimmunoglobulin material, which immunoglobulin or immunoglobulin fragment joined to a nonimmunoglobulin material is not the expression product of a gene fusion.