US PATENT SUBCLASS 552 / 502
.~ Cyclopentanohydrophenanthrene ring system containing

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552 /   HD   ORGANIC COMPOUNDS -- PART OF THE CLASS 532-570 SERIES

*  DD  ORGANIC COMPOUNDS (Class 532, subclass 1) {11}
502.~ Cyclopentanohydrophenanthrene ring system containing {21}
503  DF  .~.~> With preservative or stabilizer
504  DF  .~.~> Heavy metal or aluminum containing
505  DF  .~.~> Boron, silicon, selenium or tellurium containing
506  DF  .~.~> Phosphorus attached directly or indirectly to the cyclopentanohydrophenanthrene ring system by nonionic bonding {1}
508  DF  .~.~> Spiro
509  DF  .~.~> Plural cyclopentanohydrophenanthrene ring systems
510  DF  .~.~> The cyclopentanohydrophenanthrene ring system is part of a polycyclo ring system having at least five cyclos {4}
515  DF  .~.~> Nitrogen bonded directly to the cyclopentanohydrophenanthrene ring system {3}
523  DF  .~.~> Sulfur bonded directly to the cyclopentanohydrophenanthrene ring system {2}
526  DF  .~.~> Carbon double bonded directly to the cyclopentanohydrophenantrene ring system {3}
535  DF  .~.~> Halogen bonded directly at the 12-position of the cyclopentanohydrophenanthrene ring system
536  DF  .~.~> Halogen bonded directly at the 16-position of the cyclopentanohydrophenanthrene ring system {2}
539  DF  .~.~> Halomethyl bonded directly to the cyclopentanohydrophenanthrene ring system (e.g., 16-trifluoromethyl progesterones, etc.)
540  DF  .~.~> Carbon bonded directly at the 17 beta-position of the cyclopentanohydrophenanthrene ring system is a member of an acyclic chain of six or more uninterrupted carbons (e.g., sterols, etc.) {4}
548  DF  .~.~> Carbon bonded directly at the 17 beta-position of the cyclopentanohydrophenanthrene ring system is a member of an acyclic chain of five uninterrupted carbons (e.g., choladienes, cholanic acids, etc.) stocks, yeast, molds, etc.) {3}
553  DF  .~.~> Carbon bonded directly at the 17 beta-position of the cyclopentanohydrophenanthrene ring system is a member of an acyclic chain of three or four uninterruped carbons, (e.g., diketobisnorcholenic acids, etc.) {2}
557  DF  .~.~> Carbon bonded directly at the 17-beta-position of the cyclopentanohydrophenanthrene ring system is a member of an acyclic chain of two uninterrupted carbons (e.g., pregnanes, etc.) {4}
610  DF  .~.~> Acyclic carbon bonded directly at the 17 beta-position of the cyclopentanohydrophenanthrene ring system (e.g., etiocholanic acids, 17 cyanoetiocholanes, 17-aldehydrostanes, etc.) {1}
612  DF  .~.~> Three or more oxygens bonded directly to the cyclopentanohydrophenanthrene ring system {6}
623  DF  .~.~> Two oxygens bonded directly to the cyclopentanohydrophenanthrene ring system {5}
650  DF  .~.~> Oxygen bonded directly at the 16- or 17-position of the cyclopentanohydrophenanthrene ring system {2}

DEFINITION

Classification: 552/502

(under subclass 1) Compounds under Class 532, ..., which have the basic structure in Fig. 1 below, Which may contain double bonds between its ring members.: [figure] [caption]Figure 1.

(1) Note. The phenanthrene portion of this tetracyclic ring system cannot be completely aromatic; it must be hydrogenated

to some degree.

(2) Note. In the indents hereunder which refer to positions, the numbers shown in this definition are employed.

(3) Note. Included herein are compounds which contain an additional ring fused to one or more of the rings of the cyclopentanohydrophenanthrene ring system. See subclasses 510-514.

(4) Note. The following structure shows the numbering system for substituents at the 17-position of the cyclopentanohydrophenanthrene ring system: [figure]

(5) Note. A substituent at the 17-position of the cyclopentano-hydrophenanthrene ring system is designated as alpha or beta depending upon the stereochemical configuration thereof. A 17 beta-substituent is normally written or drawn directly above the 17-carbon atom and attached thereto by a solid line; a 17-alpha substituent is normally written or drawn to the right of the 17-carbon atom and attached thereto by dotted lines. The drawings below illustrate a cyano substituent as both a 17-beta and 17-alpha substituent. [figure] [caption]17B-cyano-3, 16a-diacetoxyestr -1,3,5(10)-trien-17a-ol [figure] [caption]17a-cyano-3, 16a-diacetoxyestra-1,3,5,(10)-trien-17B-ol SEE OR SEARCH THIS CLASS, SUBCLASS:

653, for Vitamin D compounds, calciferols, cholecalciferols, ergocalciferols, activated ergosterols, activated 7-dehydrocholesterols, irradiated ergosterol, irradiated 7-dehydrocholesterol, antirachitic vitamins, dihydrotachysterols, and 3,5-cyclovitamin D compounds.

SEE OR SEARCH CLASS

514, Drug, Bio-Affecting and Body Treating Compositions,

169+, for a medicinal composition including a cyclopentanohydrophenanthrene compound.

536, Organic Compounds,

5+, for steroid glucosides, e.g., digitalis glucosides.

540, Organic Compounds,

2+, for cyclopentanohydrophenanthrene compounds containing a heterocyclic nucleus.