US PATENT SUBCLASS 540 / 323
.~.~.~.~.~.~.~.~.~.~.~ Base salt formation of 3-position -COOH group


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540 /   HD   ORGANIC COMPOUNDS -- PART OF THE CLASS 532-570 SERIES

*  DD  ORGANIC COMPOUNDS (Class 532, Subclass 1) {1}
1  DF  .~ HETEROCYCLIC CARBON COMPOUNDS CONTAINING A HETERO RING HAVING CHALCOGEN (I.E., OXYGEN, SULFUR, SELENIUM OR TELLURIUM) OR NITROGEN AS THE ONLY RING HETERO ATOMS {6}
200  DF  .~.~ Hetero ring is four-membered containing nitrogen and having chalcogen double bonded directly to a ring carbon which is adjacent to the ring nitrogen {7}
203  DF  .~.~.~ Polycyclo ring system containing the hetero ring as one of the cyclos {4}
302  DF  .~.~.~.~ The ring nitrogen is shared by a five-membered ring {2}
303  DF  .~.~.~.~.~ The five-membered ring contains an additional hetero atom {2}
304  DF  .~.~.~.~.~.~ 1-thia-4-aza-bicyclo(3.2.0)hep-tane (including unsaturated; e.g., penam, etc.) {6}
310  DF  .~.~.~.~.~.~.~ Having -C(=X)-, wherein X is chalcogen, bonded directly at the 3-position of the bicyclo ring system {2}
312  DF  .~.~.~.~.~.~.~.~ Nitrogen bonded directly at the 6-position of the bicyclo ring system {3}
314  DF  .~.~.~.~.~.~.~.~.~ Having -C(=X)-, wherein X is chalcogen, single bonded directly to the nitrogen (e.g., penicillin F, etc.) {9}
315  DF  .~.~.~.~.~.~.~.~.~.~ Processes utilizing penam containing compound {8}
323.~.~.~.~.~.~.~.~.~.~.~ Base salt formation of 3-position -COOH group


DEFINITION

Classification: 540/323

(under subclass 315) Process whereby a base salt of penam compound is formed.

(1) Note. The penam compound represents the acidic moiety in the salt formation; therefore, included herein are those processes directed to the preparation of penicillin salts, such as, the triethyl amine salt of penicllin G, the sodium salt of penicillin X, etc.