US PATENT SUBCLASS 435 / 336
.~.~.~ Binds a hormone or other secreted growth regulatory factor, differentiation factor, intercellular mediator, or neurotransmitter (e.g., insulin, human chorionic gonadotropin, intragonadal regulatory protein, Mullerian inhibiting substance, inhibin, epidermal growth factor, nerve growth factor, dopamine, norepinephrine, etc.)

Current as of: June, 1999
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435 /   HD   CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY

325  DF  ANIMAL CELL, PER SE (E.G., CELL LINES, ETC.); COMPOSITION THEREOF; PROCESS OF PROPAGATING, MAINTAINING OR PRESERVING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF ISOLATING OR SEPARATING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF PREPARING A COMPOSITION CONTAINING AN ANIMAL CELL; CULTURE MEDIA THEREFORE {17}
326  DF  .~ Animal cell, per se, expressing immunoglobulin, antibody, or fragment thereof {7}
332  DF  .~.~ Immunoglobulin or antibody binds a microorganism or normal or mutant component or product thereof (e.g., animal cell, cell surface antigen, secretory product, etc.) {12}
336.~.~.~ Binds a hormone or other secreted growth regulatory factor, differentiation factor, intercellular mediator, or neurotransmitter (e.g., insulin, human chorionic gonadotropin, intragonadal regulatory protein, Mullerian inhibiting substance, inhibin, epidermal growth factor, nerve growth factor, dopamine, norepinephrine, etc.)

DEFINITION

Classification: 435/336

Binds a hormone or other secreted growth regulatory factor, differentiation factor, intercellular mediator, or neurotransmitter (e.g., insulin, human chorionic gonadotropin, intragonadal regulatory protein, Mullerian inhibiting substance, inhibin, epidermal growth factor, nerve growth factor, dopamine, norepinephrine, etc.):

(under subclass 332) Subject matter involving an animal cell which produces a monoclonal antibody or antigen-binding fragment thereof whose antigen-binding site(s) will combine with a neurotransmitter, with a hormone, or with any other secreted growth regulatory factor, differentiation factor, or intercellular mediator that targets cells other than hematopoietic cells.

(1) Note. The term "growth regulatory factor" is meant to encompass any secretory factor that is growth-stimulatory or growth-inhibitory; i.e., that will stimulate or inhibit clonal expansion of cells.

(2) Note. The term "differentiation factor" is meant to encompass any secretory factor that causes cells to progress from a relatively undifferentiated state to a more differentiated state, wherein said progression may include clonal expansion.

(3) Note. The term "intercellular mediator" is meant to encompass any secretory factor that affects cellular functions such as chemotaxis, etc.