US PATENT SUBCLASS 435 / 335-- .~.~.~ Binds a lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, intercellular mediator specific for a hematopoietic cell (e.g., interleukin, interferon, erythropoietin, etc.)

US PATENT SUBCLASS 435 / 335
.~.~.~ Binds a lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, intercellular mediator specific for a hematopoietic cell (e.g., interleukin, interferon, erythropoietin, etc.)

Current as of: June, 1999
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435 /	HD	CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY

325	DF	ANIMAL CELL, PER SE (E.G., CELL LINES, ETC.); COMPOSITION THEREOF; PROCESS OF PROPAGATING, MAINTAINING OR PRESERVING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF ISOLATING OR SEPARATING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF PREPARING A COMPOSITION CONTAINING AN ANIMAL CELL; CULTURE MEDIA THEREFORE {17}
326	DF	.~ Animal cell, per se, expressing immunoglobulin, antibody, or fragment thereof {7}
332	DF	.~.~ Immunoglobulin or antibody binds a microorganism or normal or mutant component or product thereof (e.g., animal cell, cell surface antigen, secretory product, etc.) {12}
335		.~.~.~ Binds a lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, intercellular mediator specific for a hematopoietic cell (e.g., interleukin, interferon, erythropoietin, etc.)

DEFINITION

Classification: 435/335

Binds a lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, intercellular mediator specific for a hematopoietic cell (e.g., interleukin, interferon, erythropoietin, etc.):

(under subclass 332) Subject matter involving an animal cell which produces a monoclonal antibody or antigen-binding fragment thereof whose antigen-binding site(s) will combine with a lymphokine, cytokine, or any other secreted growth stimulatory factor, growth inhibitory factor, differentiation factor, or intercellular mediator that targets any type(s) of hematopoietic cell(s).

(1) Note. The term "growth regulatory factor" is meant to encompass any secretory factor that is growth-stimulatory or growth-inhibitory; i.e., that will stimulate or inhibit clonal expansion of cells.

(2) Note. The term "differentiation factor" is meant to encompass any secretory factor that causes cells to progress from a relatively undifferentiated state to a more differentiated state, wherein said progression may include clonal expansion.

(3) Note. The term "intercellular mediator" is meant to encompass any secretory factor that affects cellular functions such as chemotaxis, etc.

(4) Note. See Class 424, subclass 85.1 definitions for examples of lymphokines and cytokines.

(5) Note. Hematopoietic cells are considered to be bone marrow stem cells and cells derived from bone marrow stem cells, including cells at any stage of differentiation from progenitor cells to mature erythrocytes, granulocytes, lymphocytes, etc., both normal and neoplastic.