US PATENT SUBCLASS 424 / 1.45
.~ Attached to cyclopentano-hydrophenanthrene (e.g., cholesterol, bile acid, steroids, cholane), hormone, or neurotransmitter, or other secreted growth regulatory factor, differentiation factor, or intercellular mediator (e.g., T3, T4, insulin, human chorionic gonadotropin, intragonadal regulatory protein, Mullerian inhibiting substance, inhibin, epidermal growth factor, nerve growth factor, dopamine, norepinephrine); derivative thereof

Current as of: June, 1999
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424 /   HD   DRUG, BIO-AFFECTING AND BODY TREATING COMPOSITIONS

1.11  DF  RADIONUCLIDE OR INTENDED RADIONUCLIDE CONTAINING; ADJUVANT OR CARRIER COMPOSITIONS; INTERMEDIATE OR PREPARATORY COMPOSITIONS {11}
1.45.~ Attached to cyclopentano-hydrophenanthrene (e.g., cholesterol, bile acid, steroids, cholane), hormone, or neurotransmitter, or other secreted growth regulatory factor, differentiation factor, or intercellular mediator (e.g., T3, T4, insulin, human chorionic gonadotropin, intragonadal regulatory protein, Mullerian inhibiting substance, inhibin, epidermal growth factor, nerve growth factor, dopamine, norepinephrine); derivative thereof

DEFINITION

Classification: 424/1.45

Attached to cyclopentano-hydrophenanthrene (e.g., cholesterol, bile acid, steroids, cholane), hormone, or neurotransmitter, or other secreted growth regulatory factor, differentiation factor, or intercellular mediator (e.g., T3, T4, insulin, human chorionic gonadotropin, intragonadal regulatory protein, Mullerian inhibiting substance, inhibin, epidermal growth factor, nerve growth factor, dopamine, norepinephrine); derivative thereof:

(under subclass 1.11) Subject matter in which the radionuclide or intended radionuclide is attached (bonded, chelated, complexed) to a cyclopentano-hydrophenanthrene (e.g., cholesterol), hormone, or neurotransmitter, or any other secreted growth regulatory factor, differentiation factor or intercellular mediator, or derivative thereof, that targets cells other than hematopoietic cells; and the derivatives thereof.

(1) Note. The term "growth regulatory factor" is meant to encompass any secretory factor that is growth-stimulatory or growth-inhibitory (i.e., that will stimulate or inhibit cluneal expansion of cells).

(2) Note. The term "differentiation factor" is meant to encompass any secretory factor that causes cells to progress from a relatively undifferentiated state to a more differentiated state, wherein said progression may include cluneal expansion.

(3) Note. The term "intercellular mediator" is meant to encompass any secretory factor that affects cellular functions such as chemotaxis, etc.

(4) Note. Cyclopentano-hydrophenanthrene or a derivative thereof means those compounds which do not destroy the 17 carbon atoms forming the four-fused-ring structure. The four-fused-ring structure need not contain the same number of hydrogen atoms or double bonds to be proper for placement here. The necessary requirement is that the 17 carbons atoms retain the relationship exhibited in the base compound.

SEE OR SEARCH THIS CLASS, SUBCLASS:

1.21, for liposomes containing cholesterol and derivatives within the liposome or liposome bilayer. SEE OR SEARCH CLASS

552, Organic Compounds, for per se cyclopentano-hydrophenanthrene and derivatives thereof.